Small molecule can take apart Alzheimer's disease
protein fibers

post from Science Blog - Send lawyers, guns and money on 16 May 2008 10:18:14 AM. © Science Blog - Send lawyers, guns and money

Researchers from the University of Pennsylvania School of Medicine have shown, in unprecedented detail, how a small molecule is able to selectively take apart abnormally folded protein fibers connected to Alzheimer's disease and prion diseases. The findings appear online this week in the Proceedings of the National Academy of Sciences. Finding a way to dismantle misfolded proteins has implications for new treatments for a host of neurodegenerative diseases.

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